The UMD-MEN1 mutations database
Ser to Leu mutations

Protein nomenclature	cDNA Nomenclature	Exon	Codon	Structure	HCD	Rearrangement	Mutation type	Mutational event	# records
p.Ser253Leu	c.758C>T	4	253	Sm,NM,NMH,FA,HD		Small rearrangement	Ts	C->T	4
UMD_id Sample ID Gender Mutation status Variation class Family ID References 1942 04-OL19-M09-994 Female CAUSAL 0 1941 04-TH01-J05-953 Male CAUSAL 0 1919 04-ES20-M01-959 Female LIKELY CAUSAL 0 1878 04-ES20-M01R-959 Female Heterozygous LIKELY CAUSAL 43
p.Ser512Leu	c.1535C>T	10	512	Sm3,CH		Small rearrangement	Ts	C->T	2
UMD_id Sample ID Gender Mutation status Variation class Family ID References 1894 04-PA21-M01M-956 Female Heterozygous LIKELY NEUTRAL 0 1668 02-WE18-M09C-959 Female Heterozygous LIKELY NEUTRAL 0
p.Ser572Leu	c.1715C>T	10	572	Sm,ASK,CH		Small rearrangement	Ts	C->T	1
UMD_id Sample ID Gender Mutation status Variation class Family ID References 1977 01-GR09-F01-970 Female UV 0