The UMD-MEN1 mutations database
Pro to Leu mutations

Protein nomenclature	cDNA Nomenclature	Exon	Codon	Structure	HCD	Rearrangement	Mutation type	Mutational event	# records
p.Pro188Leu	c.563C>T	3	188	Ju,Sm,NMH,HD,NM		Small rearrangement	Ts	C->T	1
UMD_id Sample ID Gender Mutation status Variation class Family ID References 508 03-DU18-D26E-970 Male Heterozygous UV 0
p.Pro277Leu	c.830C>T	6	277	Sm,NM,NMH,FA,HD		Small rearrangement	Ts	C->T	5
UMD_id Sample ID Gender Mutation status Variation class Family ID References 1779 02-BO14-J05A-952 Male Heterozygous CAUSAL W2043 0 106 04-CO18-I07N-969 Male Heterozygous CAUSAL 0 697 03-BO14-A21D-979 Male Heterozygous CAUSAL W2043 0 1345 01-DE12-S05B-979 Male Heterozygous CAUSAL W229 0 1346 01-MO18-G05N-947 Female Heterozygous CAUSAL W229 0
p.Pro320Leu	c.959C>T	7	320	NF,NM,RP,FA,HD		Small rearrangement	Ts	C->T	1
UMD_id Sample ID Gender Mutation status Variation class Family ID References 1623 02-CH05-Y21N-971 Female Heterozygous CAUSAL 35
p.Pro470Leu	c.1409C>T	10	470	Pem,NM,CH		Small rearrangement	Ts	C->T	1
UMD_id Sample ID Gender Mutation status Variation class Family ID References 1975 04-VE18-I19-984 Male NEUTRAL 0
p.Pro514Leu	c.1541C>T	10	514	Sm3,CH		Small rearrangement	Ts	C->T	1
UMD_id Sample ID Gender Mutation status Variation class Family ID References 1192 03-MA26-A13A-978 Female Heterozygous LIKELY NEUTRAL W12 0