The UMD-DMD France mutations database
Impact of mutations on dystrophin isoforms

This function predicts the impact of mutations on the various isoforms of the dystrophin.

Dp427c = cerebral isoform of the 427 kD dystrophin; Dp427m = muscular isoform of the 427 kD dystrophin; Dp427p = purkinje isoform of the 427 kD dystrophin; Dp260 = retinal 260 kD dystrophin isoform; Dp140 = CNS 140 kD dystrophin isoform; Dp116 = Schwann cells 116 kD dystrophin isoform and Dp71 = 71 kD ubiquitous (except muscle) dystrophin isoform.

MutationDp427cDp427mDp427pDp260Dp140Dp116Dp71
Large duplication from exon 1 to exon 0        
Large deletion from exon 1 to exon 1        
Large duplication from exon 1 to exon 1        
Large deletion from exon 1 to exon 2        
Large deletion from exon 1 to exon 7        
Large deletion from exon 1 to exon 8        
Large deletion from exon 1 to exon 9        
Large deletion from exon 1 to exon 16        
Large deletion from exon 1 to exon 30        
Large deletion from exon 1 to exon 43        
Large deletion from exon 1 to exon 44        
Large deletion from exon 1 to exon 49        
Large deletion from exon 1 to exon 51        
Large deletion from exon 1 to exon 79        
Large duplication from exon 2 to exon 2        
Large duplication from exon 2 to exon 4        
Large deletion from exon 2 to exon 6        
Large deletion from exon 2 to exon 7        
Large duplication from exon 2 to exon 7        
Large duplication from exon 2 to exon 9        
Large duplication from exon 2 to exon 11        
Large deletion from exon 2 to exon 12        
Large duplication from exon 2 to exon 12        
Large duplication from exon 2 to exon 13        
Large duplication from exon 2 to exon 16        
Large deletion from exon 2 to exon 17        
Large duplication from exon 2 to exon 18        
Large duplication from exon 2 to exon 34        
Large duplication from exon 2 to exon 41        
Large duplication from exon 2 to exon 44        
Large deletion from exon 2 to exon 60        
Large deletion from exon 3 to exon 3        
Large duplication from exon 3 to exon 3        
Large deletion from exon 3 to exon 4        
Large duplication from exon 3 to exon 4        
Large deletion from exon 3 to exon 5        
Large duplication from exon 3 to exon 5        
Large deletion from exon 3 to exon 6        
Large duplication from exon 3 to exon 6        
Large deletion from exon 3 to exon 7        
Large duplication from exon 3 to exon 7        
Large deletion from exon 3 to exon 8        
Large deletion from exon 3 to exon 9        
Large duplication from exon 3 to exon 9        
Large deletion from exon 3 to exon 11        
Large duplication from exon 3 to exon 11        
Large deletion from exon 3 to exon 12        
Large duplication from exon 3 to exon 12        
Large deletion from exon 3 to exon 13        
Large deletion from exon 3 to exon 15        
Large deletion from exon 3 to exon 16        
Large duplication from exon 3 to exon 16        
Large deletion from exon 3 to exon 17        
Large duplication from exon 3 to exon 17        
Large deletion from exon 3 to exon 18        
Large deletion from exon 3 to exon 19        
Large duplication from exon 3 to exon 19        
Large deletion from exon 3 to exon 20        
Large deletion from exon 3 to exon 21        
Large duplication from exon 3 to exon 21        
Large deletion from exon 3 to exon 25        
Large duplication from exon 3 to exon 26        
Large deletion from exon 3 to exon 27        
Large deletion from exon 3 to exon 29        
Large deletion from exon 3 to exon 30        
Large deletion from exon 3 to exon 33        
Large deletion from exon 3 to exon 34        
Large deletion from exon 3 to exon 37        
Large deletion from exon 3 to exon 41        
Large duplication from exon 3 to exon 42        
Large deletion from exon 3 to exon 43        
Large deletion from exon 3 to exon 44        
Large deletion from exon 3 to exon 49        
Large deletion from exon 3 to exon 54        
Large duplication from exon 4 to exon 4        
Large deletion from exon 4 to exon 7        
Large duplication from exon 4 to exon 7        
Large duplication from exon 4 to exon 8        
Large deletion from exon 4 to exon 12        
Large deletion from exon 4 to exon 13        
Large deletion from exon 4 to exon 21        
Large duplication from exon 5 to exon 5        
Large deletion from exon 5 to exon 7        
Large duplication from exon 5 to exon 7        
Large deletion from exon 5 to exon 9        
Large duplication from exon 5 to exon 10        
Large deletion from exon 5 to exon 11        
Large duplication from exon 5 to exon 11        
Large duplication from exon 5 to exon 12        
Large deletion from exon 5 to exon 17        
Large duplication from exon 5 to exon 17        
Large deletion from exon 5 to exon 18        
Large duplication from exon 5 to exon 21        
Large deletion from exon 5 to exon 42        
Large deletion from exon 5 to exon 48        
Large deletion from exon 6 to exon 7        
Large duplication from exon 6 to exon 7        
Large deletion from exon 6 to exon 10        
Large deletion from exon 6 to exon 12        
Large deletion from exon 6 to exon 13        
Large deletion from exon 7 to exon 7        
Large duplication from exon 7 to exon 7        
Large deletion from exon 7 to exon 11        
Large deletion from exon 7 to exon 13        
Large duplication from exon 7 to exon 15        
Large deletion from exon 8 to exon 8        
Large deletion from exon 8 to exon 9        
Large duplication from exon 8 to exon 9        
Large deletion from exon 8 to exon 11        
Large duplication from exon 8 to exon 11        
Large deletion from exon 8 to exon 12        
Large duplication from exon 8 to exon 12        
Large deletion from exon 8 to exon 13        
Large duplication from exon 8 to exon 13        
Large deletion from exon 8 to exon 15        
Large duplication from exon 8 to exon 15        
Large deletion from exon 8 to exon 16        
Large duplication from exon 8 to exon 16        
Large deletion from exon 8 to exon 17        
Large duplication from exon 8 to exon 17        
Large deletion from exon 8 to exon 18        
Large duplication from exon 8 to exon 18        
Large deletion from exon 8 to exon 19        
Large deletion from exon 8 to exon 23        
Large duplication from exon 8 to exon 23        
Large deletion from exon 8 to exon 25        
Large deletion from exon 8 to exon 27        
Large deletion from exon 8 to exon 29        
Large deletion from exon 8 to exon 30        
Large deletion from exon 8 to exon 37        
Large deletion from exon 8 to exon 42        
Large deletion from exon 8 to exon 43        
Large deletion from exon 8 to exon 44        
Large deletion from exon 10 to exon 11        
Large duplication from exon 10 to exon 11        
Large deletion from exon 10 to exon 12        
Large deletion from exon 10 to exon 13        
Large deletion from exon 10 to exon 16        
Large deletion from exon 10 to exon 17        
Large duplication from exon 10 to exon 17        
Large deletion from exon 10 to exon 18        
Large duplication from exon 10 to exon 19        
Large deletion from exon 10 to exon 21        
Large duplication from exon 10 to exon 21        
Large deletion from exon 10 to exon 28        
Large deletion from exon 10 to exon 29        
Large deletion from exon 10 to exon 30        
Large deletion from exon 10 to exon 34        
Large duplication from exon 10 to exon 37        
Large deletion from exon 10 to exon 38        
Large deletion from exon 10 to exon 41        
Large deletion from exon 10 to exon 42        
Large deletion from exon 10 to exon 43        
Large deletion from exon 10 to exon 44        
Large duplication from exon 11 to exon 11        
Large deletion from exon 11 to exon 18        
Large deletion from exon 11 to exon 27        
Large deletion from exon 11 to exon 29        
Large deletion from exon 11 to exon 30        
Large deletion from exon 11 to exon 37        
Large deletion from exon 11 to exon 41        
Large deletion from exon 12 to exon 12        
Large deletion from exon 12 to exon 13        
Large duplication from exon 12 to exon 13        
Large deletion from exon 12 to exon 16        
Large duplication from exon 12 to exon 16        
Large deletion from exon 12 to exon 18        
Large deletion from exon 12 to exon 22        
Large deletion from exon 12 to exon 29        
Large duplication from exon 12 to exon 29        
Large deletion from exon 12 to exon 41        
Large deletion from exon 12 to exon 42        
Large deletion from exon 12 to exon 44        
Large deletion from exon 12 to exon 51        
Large deletion from exon 12 to exon 55        
Large duplication from exon 13 to exon 16        
Large deletion from exon 13 to exon 19        
Large deletion from exon 13 to exon 29        
Large deletion from exon 13 to exon 30        
Large deletion from exon 13 to exon 37        
Large deletion from exon 13 to exon 41        
Large deletion from exon 13 to exon 43        
Large deletion from exon 13 to exon 44        
Large deletion from exon 13 to exon 51        
Large deletion from exon 14 to exon 17        
Large duplication from exon 14 to exon 17        
Large duplication from exon 14 to exon 18        
Large duplication from exon 14 to exon 29        
Large deletion from exon 14 to exon 41        
Large deletion from exon 14 to exon 43        
Large duplication from exon 14 to exon 44        
Large duplication from exon 16 to exon 27        
Large duplication from exon 16 to exon 44        
Large deletion from exon 17 to exon 17        
Large duplication from exon 17 to exon 17        
Large deletion from exon 17 to exon 21        
Large deletion from exon 17 to exon 24        
Large deletion from exon 17 to exon 29        
Large deletion from exon 17 to exon 34        
Large deletion from exon 17 to exon 43        
Large duplication from exon 17 to exon 44        
Large deletion from exon 18 to exon 18        
Large deletion from exon 18 to exon 19        
Large deletion from exon 18 to exon 21        
Large deletion from exon 18 to exon 26        
Large duplication from exon 18 to exon 27        
Large duplication from exon 18 to exon 28        
Large duplication from exon 18 to exon 29        
Large deletion from exon 18 to exon 34        
Large duplication from exon 18 to exon 34        
Large deletion from exon 18 to exon 43        
Large deletion from exon 18 to exon 44        
Large duplication from exon 18 to exon 44        
Large deletion from exon 19 to exon 19        
Large duplication from exon 19 to exon 19        
Large deletion from exon 19 to exon 21        
Large duplication from exon 19 to exon 30        
Large duplication from exon 19 to exon 43        
Large deletion from exon 19 to exon 44        
Large duplication from exon 19 to exon 44        
Large duplication from exon 19 to exon 51        
Large duplication from exon 20 to exon 20        
Large deletion from exon 20 to exon 25        
Large duplication from exon 20 to exon 26        
Large deletion from exon 20 to exon 39        
Large deletion from exon 20 to exon 41        
Large duplication from exon 20 to exon 43        
Large deletion from exon 20 to exon 44        
Large deletion from exon 20 to exon 47        
Large deletion from exon 21 to exon 21        
Large duplication from exon 21 to exon 55        
Large duplication from exon 22 to exon 23        
Large deletion from exon 22 to exon 29        
Large deletion from exon 22 to exon 30        
Large duplication from exon 22 to exon 33        
Large deletion from exon 22 to exon 34        
Large deletion from exon 22 to exon 41        
Large deletion from exon 22 to exon 43        
Large deletion from exon 22 to exon 44        
Large deletion from exon 23 to exon 44        
Large deletion from exon 26 to exon 28        
Large deletion from exon 26 to exon 30        
Large deletion from exon 26 to exon 43        
Large duplication from exon 27 to exon 34        
Large deletion from exon 27 to exon 43        
Large deletion from exon 27 to exon 44        
Large deletion from exon 28 to exon 44        
Large duplication from exon 28 to exon 46        
Large deletion from exon 29 to exon 43        
Large duplication from exon 29 to exon 43        
Large deletion from exon 30 to exon 34        
Large deletion from exon 30 to exon 43        
Large duplication from exon 30 to exon 44        
Large deletion from exon 31 to exon 43        
Large deletion from exon 31 to exon 45        
Large deletion from exon 32 to exon 43        
Large deletion from exon 34 to exon 34        
Large deletion from exon 35 to exon 42        
Large deletion from exon 35 to exon 44        
Large duplication from exon 35 to exon 55        
Large deletion from exon 36 to exon 46        
Large deletion from exon 38 to exon 43        
Large deletion from exon 38 to exon 44        
Large deletion from exon 39 to exon 43        
Large deletion from exon 40 to exon 43        
Large deletion from exon 40 to exon 44        
Large deletion from exon 41 to exon 41        
Large deletion from exon 41 to exon 43        
Large deletion from exon 42 to exon 43        
Large deletion from exon 43 to exon 43        
Large duplication from exon 43 to exon 43        
Large deletion from exon 43 to exon 45        
Large duplication from exon 43 to exon 47        
Large deletion from exon 43 to exon 50        
Large deletion from exon 44 to exon 44        
Large duplication from exon 44 to exon 44        
Large deletion from exon 44 to exon 47        
Large duplication from exon 44 to exon 49        
Large deletion from exon 44 to exon 51        
Large deletion from exon 44 to exon 52        
Large duplication from exon 44 to exon 52        
Large deletion from exon 44 to exon 53        
Large duplication from exon 44 to exon 53        
Large deletion from exon 44 to exon 55        
Large duplication from exon 44 to exon 55        
Large duplication from exon 44 to exon 59        
Large deletion from exon 44 to exon 60        
Large deletion from exon 45 to exon 45        
Large duplication from exon 45 to exon 45        
Large deletion from exon 45 to exon 46        
Large deletion from exon 45 to exon 47        
Large duplication from exon 45 to exon 47        
Large deletion from exon 45 to exon 48        
Large deletion from exon 45 to exon 49        
Large duplication from exon 45 to exon 49        
Large deletion from exon 45 to exon 50        
Large duplication from exon 45 to exon 50        
Large deletion from exon 45 to exon 51        
Large deletion from exon 45 to exon 52        
Large deletion from exon 45 to exon 53        
Large deletion from exon 45 to exon 54        
Large deletion from exon 45 to exon 55        
Large duplication from exon 45 to exon 55        
Large deletion from exon 45 to exon 57        
Large duplication from exon 45 to exon 60        
Large duplication from exon 45 to exon 62        
Large deletion from exon 45 to exon 79        
Large deletion from exon 46 to exon 46        
Large deletion from exon 46 to exon 47        
Large duplication from exon 46 to exon 47        
Large deletion from exon 46 to exon 48        
Large deletion from exon 46 to exon 49        
Large deletion from exon 46 to exon 50        
Large deletion from exon 46 to exon 51        
Large deletion from exon 46 to exon 52        
Large deletion from exon 46 to exon 53        
Large deletion from exon 46 to exon 55        
Large duplication from exon 46 to exon 55        
Large deletion from exon 46 to exon 79        
Large deletion from exon 47 to exon 47        
Large deletion from exon 47 to exon 48        
Large deletion from exon 47 to exon 49        
Large deletion from exon 47 to exon 50        
Large deletion from exon 47 to exon 51        
Large deletion from exon 47 to exon 52        
Large deletion from exon 48 to exon 48        
Large deletion from exon 48 to exon 49        
Large duplication from exon 48 to exon 49        
Large deletion from exon 48 to exon 50        
Large duplication from exon 48 to exon 50        
Large deletion from exon 48 to exon 51        
Large deletion from exon 48 to exon 52        
Large deletion from exon 48 to exon 53        
Large deletion from exon 48 to exon 54        
Large duplication from exon 48 to exon 54        
Large deletion from exon 48 to exon 55        
Large deletion from exon 48 to exon 57        
Large deletion from exon 48 to exon 59        
Large duplication from exon 48 to exon 61        
Large duplication from exon 48 to exon 63        
Large duplication from exon 48 to exon 77        
Large deletion from exon 49 to exon 49        
Large deletion from exon 49 to exon 50        
Large duplication from exon 49 to exon 50        
Large deletion from exon 49 to exon 51        
Large deletion from exon 49 to exon 52        
Large deletion from exon 49 to exon 54        
Large deletion from exon 49 to exon 61        
Large deletion from exon 49 to exon 79        
Large deletion from exon 50 to exon 50        
Large duplication from exon 50 to exon 50        
Large deletion from exon 50 to exon 51        
Large deletion from exon 50 to exon 52        
Large duplication from exon 50 to exon 53        
Large deletion from exon 50 to exon 54        
Large duplication from exon 50 to exon 55        
Large duplication from exon 50 to exon 56        
Large deletion from exon 50 to exon 58        
Large duplication from exon 50 to exon 60        
Large duplication from exon 50 to exon 61        
Large duplication from exon 50 to exon 62        
Large deletion from exon 50 to exon 79        
Large deletion from exon 51 to exon 51        
Large duplication from exon 51 to exon 51        
Large deletion from exon 51 to exon 52        
Large deletion from exon 51 to exon 53        
Large deletion from exon 51 to exon 54        
Large deletion from exon 51 to exon 55        
Large duplication from exon 51 to exon 55        
Large deletion from exon 51 to exon 56        
Large duplication from exon 51 to exon 60        
Large deletion from exon 51 to exon 76        
Large deletion from exon 52 to exon 52        
Large duplication from exon 52 to exon 52        
Large deletion from exon 52 to exon 54        
Large duplication from exon 52 to exon 54        
Large deletion from exon 52 to exon 55        
Large duplication from exon 52 to exon 59        
Large duplication from exon 52 to exon 61        
Large deletion from exon 52 to exon 62        
Large duplication from exon 52 to exon 62        
Large deletion from exon 52 to exon 63        
Large deletion from exon 52 to exon 79        
Large deletion from exon 53 to exon 53        
Large duplication from exon 53 to exon 53        
Large deletion from exon 53 to exon 54        
Large duplication from exon 53 to exon 54        
Large deletion from exon 53 to exon 55        
Large duplication from exon 53 to exon 55        
Large duplication from exon 53 to exon 60        
Large deletion from exon 53 to exon 79        
Large deletion from exon 54 to exon 54        
Large duplication from exon 54 to exon 55        
Large duplication from exon 54 to exon 59        
Large deletion from exon 55 to exon 55        
Large duplication from exon 55 to exon 55        
Large duplication from exon 55 to exon 59        
Large duplication from exon 55 to exon 60        
Large deletion from exon 55 to exon 61        
Large deletion from exon 55 to exon 79        
Large deletion from exon 56 to exon 56        
Large duplication from exon 56 to exon 60        
Large duplication from exon 56 to exon 61        
Large duplication from exon 56 to exon 62        
Large deletion from exon 56 to exon 76        
Large deletion from exon 58 to exon 58        
Large deletion from exon 58 to exon 61        
Large duplication from exon 58 to exon 62        
Large duplication from exon 60 to exon 61        
Large duplication from exon 60 to exon 62        
Large deletion from exon 60 to exon 63        
Large duplication from exon 60 to exon 66        
Large deletion from exon 60 to exon 79        
Large deletion from exon 61 to exon 61        
Large deletion from exon 61 to exon 62        
Large deletion from exon 61 to exon 67        
Large deletion from exon 61 to exon 69        
Large deletion from exon 61 to exon 79        
Large deletion from exon 62 to exon 62        
Large duplication from exon 62 to exon 62        
Large deletion from exon 63 to exon 63        
Large deletion from exon 63 to exon 64        
Large duplication from exon 63 to exon 67        
Large deletion from exon 63 to exon 79        
Large duplication from exon 63 to exon 79        
Large deletion from exon 64 to exon 64        
Large deletion from exon 65 to exon 65        
Large deletion from exon 66 to exon 67        
Large deletion from exon 67 to exon 67        
Large deletion from exon 68 to exon 76        
Large deletion from exon 75 to exon 76