The UMD-CSB mutations database
Nucleotides modifications

This function takes into account only small rearrangements.

For each of the four bases are displayed its number in the CSB cDNA at each codon's position as well as the corresponding mutability. For each base are also displayed the various substitutions and small deletions and insertions.

	from A			from C			from G			from T
Position in codon	1st	2nd	3rd	1st	2nd	3rd	1st	2nd	3rd	1st	2nd	3rd
Number in sequence	435	553	395	330	319	300	487	271	404	242	351	395
Mutability	1305	1659	434	990	957	344	1461	788	618	726	995	444
to A	.	.	.	.	.	.	.	1	2	1	.	.
to C	.	.	.	.	.	.	.	.	1	.	2	.
to G	2	1	1	.	1	.	.	.	.	.	1	.
to T	1	.	.	24	2	.	2	.	.	.	.	.
Deletion	2	2	.	2	1	1	.	.	1	1	.	1
Insertion	2	1	1	.	.	1	2	.	.	.	.	1

Mutability: for each base, the significance of a mutation is defined by the ability to produce a new Amino Acid. In these conditions, the position of the specific base in the codon has a major incidence. If any substitution result in a new Amino Acid, its individual mutability is 3. If only two substitutions result in a new Amino Acid, its mutability is 2... The Mutability at a specific position in the codon (first base=1st, second base=2nd and third base=3rd) is defined by the addition of all individual mutability for this base in each codon of the coding sequence.