For each amino acids are displayed the number of residues in the CSB protein and its frequency; the expected number of mutations if events were randomly distributed and the observed number of mutations affecting these residues. A click on the an amino acid gives access to a detailed table of substitutions and other mutations.
A click on the "Detailed view of mutations at the AA level" will display a summary table of all events.
Amino Acid | Number in the protein | Expected number of mutations | Observed number of mutations | ||
---|---|---|---|---|---|
Ala | 93 | (6.22 %) | 4.8 | 0 | (0 %) |
Arg | 92 | (6.16 %) | 4.7 | 31 | (40.26 %) |
Asn | 53 | (3.55 %) | 2.7 | 2 | (2.6 %) |
Asp | 85 | (5.69 %) | 4.4 | 1 | (1.3 %) |
Cys | 20 | (1.34 %) | 1 | 0 | (0 %) |
Gln | 85 | (5.69 %) | 4.4 | 8 | (10.39 %) |
Glu | 126 | (8.43 %) | 6.5 | 2 | (2.6 %) |
Gly | 103 | (6.89 %) | 5.3 | 1 | (1.3 %) |
His | 40 | (2.68 %) | 2.1 | 1 | (1.3 %) |
Ile | 64 | (4.28 %) | 3.3 | 0 | (0 %) |
Leu | 128 | (8.57 %) | 6.6 | 3 | (3.9 %) |
Lys | 126 | (8.43 %) | 6.5 | 8 | (10.39 %) |
Met | 27 | (1.81 %) | 1.4 | 1 | (1.3 %) |
Phe | 52 | (3.48 %) | 2.7 | 2 | (2.6 %) |
Pro | 71 | (4.75 %) | 3.7 | 3 | (3.9 %) |
Ser | 122 | (8.17 %) | 6.3 | 1 | (1.3 %) |
Stop | 1 | (0.07 %) | 0.1 | 0 | (0 %) |
Thr | 72 | (4.82 %) | 3.7 | 1 | (1.3 %) |
Trp | 17 | (1.14 %) | 0.9 | 6 | (7.79 %) |
Tyr | 37 | (2.48 %) | 1.9 | 3 | (3.9 %) |
Val | 80 | (5.35 %) | 4.1 | 3 | (3.9 %) |