The UMD-CSB mutations database
Amino acids modifications

This function takes into account only small rearrangements.

For each amino acids are displayed the number of residues in the CSB protein and its frequency; the expected number of mutations if events were randomly distributed and the observed number of mutations affecting these residues. A click on the an amino acid gives access to a detailed table of substitutions and other mutations.
A click on the "Detailed view of mutations at the AA level" will display a summary table of all events.

Amino AcidNumber in the proteinExpected number of mutationsObserved number of mutations
Ala93(6.22 %)4.80(0 %)
Arg92(6.16 %)4.731(40.26 %)
Asn53(3.55 %)2.72(2.6 %)
Asp85(5.69 %)4.41(1.3 %)
Cys20(1.34 %)10(0 %)
Gln85(5.69 %)4.48(10.39 %)
Glu126(8.43 %)6.52(2.6 %)
Gly103(6.89 %)5.31(1.3 %)
His40(2.68 %)2.11(1.3 %)
Ile64(4.28 %)3.30(0 %)
Leu128(8.57 %)6.63(3.9 %)
Lys126(8.43 %)6.58(10.39 %)
Met27(1.81 %)1.41(1.3 %)
Phe52(3.48 %)2.72(2.6 %)
Pro71(4.75 %)3.73(3.9 %)
Ser122(8.17 %)6.31(1.3 %)
Stop1(0.07 %)0.10(0 %)
Thr72(4.82 %)3.71(1.3 %)
Trp17(1.14 %)0.96(7.79 %)
Tyr37(2.48 %)1.93(3.9 %)
Val80(5.35 %)4.13(3.9 %)

Detailed view of mutations at the AA level