The UMD-CFTR mutations database
Therapeutic approaches

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The three functions below are dedicated to the nonsens readthrough approach.

They give access to the list of all patients with a nonsens mutation that can be eligible for the nonsens readthrough therapeutic approach.

Patients with a TGA premature stop codon

This function displays the list of patients with a substitution that results in the creation of a premature TGA stop codon.

Patients with a TAG premature stop codon

This function displays the list of patients with a substitution that results in the creation of a premature TAG stop codon.

Patients with a TAA premature stop codon

This function displays the list of patients with a substitution that results in the creation of a premature TAA stop codon.