Last update 16/06/17
|This database includes
( 3454 different variations)
BRCA Share was launched on April 21st 2015
BRCA Share is a novel gene datashare initiative that provides scientists and commercial laboratory organizations around the world with open access to BRCA1 and BRCA2 genetic data. The programís goal is to accelerate research on BRCA gene mutations, particularly variants of uncertain significance, to improve the ability of clinical laboratory diagnostics to predict which individuals are at risk of developing these cancers.
Joining BRCA Share
As of June 1st 2015, registration will be required to access the UMD databases of BRCA1 and BRCA2 gene data.
How to Join BRCA Share?
• Non-commercial individual investigators and academic research organizations:
º Quickly access the BRCA Share data by agreeing to the programís user group agreement
• Commercial entities:
º Join BRCA Share through a sublicense agreement with Quest Diagnostics.
For any other questions, please email BRCAShare@QuestDiagnostics.com
For more information about BRCA Share, read the announcement
The databases of BRCA1 and BRCA2 mutations were built using the "Universal Mutation Database" tool.
If you use this database please cite: BRCA Share: A Collection of Clinical BRCA Gene Variants. Béroud, C., Letovsky, S. I., Braastad, C. D., Caputo, S. M., Beaudoux, O., Bignon, Y. J., ... & Coulet, F. (2016). Human Mutation, 37(12), 1318-1328.