The UMD-APC mutations database
Mutation c.IVS2-2A>G (c.221-2A>G)

Splice site type	Wild type sequence	CV	Mutant type sequence	CV	Variation (%)
Acceptor	tattttatttagAG	79.6 _	tattttatttggAG	50.6 _ *	-36.4 %

     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	APC	MLH1	MSH2	MSH6	MUTYH
10_APC-204---3154 P	-	-	-	-	-
33_SAT289---08-1544	-	-	-	-	-
33_SAT289---08-206	-	-	-	-	-
33_SAT289---09-1431	-	-	-	-	-
33_SAT289---09-1432	-	-	-	-	-
7_10756911484E091893	-	-	-	-	-

Biological significance	Date	Comment
Causal	28/05/14	---