The UMD-APC mutations database
Mutation c.IVS6-3C>G (c.730-3C>G)

Splice site type	Wild type sequence	CV	Mutant type sequence	CV	Variation (%)
Acceptor	ccatcttaacagAG	84.8 _	ccatcttaagagAG	74.5 _ *	-12.1 %

     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	APC	MLH1	MSH2	MSH6	MUTYH
10_APC-068---1122P	-	-	-	-	-
10_APC-068---824P	-	-	-	-	-
10_APC-085---988P	-	-	-	-	-
10_APC-85---2392P	-	-	-	-	-
10_APC-85---2395P	-	-	-	-	-
10_APC-85---3485 P	-	-	-	-	-
37_P08.137303---	-	-	-	-	-

Complementary data about this mutation

Analysis	Result	Date	Origin	PMID/dbSNP
In vitro analysis	RT-PCR: Complete loss of exon 7	22/07/13	19

Biological significance	Date	Comment
Causal	22/07/13	---