The UMD-APC mutations database
Mutation c.IVS5-2A>T (c.646-2A>T)

Splice site type	Wild type sequence	CV	Mutant type sequence	CV	Variation (%)
Acceptor	gttttattttagCG	79.9 _	gttttatttttgCG	51 _ *	-36.2 %

     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	APC	MLH1	MSH2	MSH6	MUTYH
10_APC-143---1216P	-	-	-	-	-
10_APC-143---3469 P	-	-	-	-	-
37_P11.027-E16922RNA11660	-	-	-	-	-
SO_-1072G00724G00724	-	-	-	-	-

Biological significance	Date	Comment
Causal	28/05/14	---