The UMD-APC mutations database
Mutation c.IVS9+27G>A (c.1312+27G>A)

Splice site type	Wild type sequence	CV	Mutant type sequence	CV	Variation (%)
Cryptic Acceptor?	TACATCGTAGTGCAT	43.3 _	TACATCGTAGAGCAT	72.3 _ *	40 %

     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	APC	MLH1	MSH2	MSH6	MUTYH
19_13817---13817.001	-	-	-	-	-
19_13969---13969.001	-	-	-	-	-
19_15089---15089-001	-	-	-	-	-

Complementary data about this mutation

Analysis	Result	Date	Origin	PMID/dbSNP
Co-occurrence	SMAD4: c.1479_1481del, p.Asp494del	19/09/13	19
Ex vivo analysis	Splicing reporter minigene pCas: normal splicing	19/09/13	19

Biological significance	Date	Comment
Neutral	19/09/13	---