The UMD-APC mutations database
Mutation c.IVS4-1G>A (c.532-1G>A)

Splice site type	Wild type sequence	CV	Mutant type sequence	CV	Variation (%)
Acceptor	ttgtggttttagTT	78.5 _	ttgtggttttaaTT	49.5 _ *	-36.9 %

     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	APC	MLH1	MSH2	MSH6	MUTYH
10_APC-190---2834 P	-	-	-	-	-
19_1427---1427.001	-	-	-	-	-
19_1427---1427.003	-	-	-	-	-
SO_-1241G00535G00535	-	-	-	-	-
SO_-613G05320G05320	-	-	-	-	-

Biological significance	Date	Comment
Causal	28/05/14	---